ClustalXeed - Cloud Computing

       Web source: http://portal.eqentia.com/cloudcomputing/source/13027-BioMed-Central

Timeline of Clustal* Series -Cute and Compressed View

The history of Clustal Series...
[web source: http://www.dipity.com/timeline/Clustalw]

Timeline of Clustal Series

Accurate and Fast MSA tool may accelerate the discovery of mitochondrial DNA mutations

Does strong hypertrophic condition induce fast mitochondrial
DNA mutation of rabbit heart?

Homo- and heteroplasmic mitochondrial DNA (mtDNA) mutations were observed and identified in an isoproterenol-induced rabbit model of cardiac hypertrophy. Genes encoding proteins essential for catalyzing mitochondrial electron transfer and for generating the proton motive force, such as NADH dehydrogenases (ND2, ND3, ND4, and ND6), cytochrome b, and ATPase 8, showed increased susceptibility for mutation. Specifically, five mutations caused amino acid changes and were located in Complex I and Complex V gene clusters. To our knowledge, this is the first demonstration of a relationship between cardiac hypertrophy induced by a strong sympathetic load and rapid mtDNA mutations.

Ref: T. Kim et al. Mitochondrion 8 (2008) 279.283

Application of in silico sequence homology searching

A putative prokaryotic inward rectifier K+ (Kir) channel
was discovered by in silico sequence homology and membrane topology analyses with respect to the number of transmembrane domains (TMs) and the presence of K+ selectivity filter and/or ATP binding sites..

New Kir6.2 Channel Discovered

Ref: The Journal of Microbiology (2010) Vol. 48, No. 3, pp. 325-330

Are you suffer from huge Phylogenetic Tree Drawing?

ClustalXeed provides a scalable vector graphics option for big tree drawing...

Data-Intensive Bioinformatics needs Supercomputing

ClustalXeed, the developer: Taeho Kim and Hyun Joo

The Test Machine: 64 bit dual Opteron Core x 100 +Gibabit Network

Professor: Hyun Joo, E-mail: phyjoo@inje.ac.kr
Deaprtment of Physiology, College of Medicine,
Inje University, Busan 614-735, Republic of Korea.

Dr. Taeho Kim, E-mail: tkim@ifrec.osaka-u.ac.jp
Laboratory of Systems Immunology,
World Premier International Immunology Frontier Research Center,
Osaka University, Suita, Osaka 565-0871, Japan.

PCHM: A bioinformatic resource for high-throughput human mitochondrial proteome searching and comparison.

PCHM inside..

[click to enlarged view]

PCHM Database - Powered by ClustalXeed...

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Site. http://pchm.inje.ac.kr/

ClustalXeed: a GUI-powered next generation sequencing analysis software

Screenshots of ClustalXeed - click PIC to enlarge

ClustalXeed is a standalone high-performance and data-intensive biological sequence analysis tool. Especially, ClustalXeed is suited for "Next-Generation Sequencing Technologies" since ClustalXeed can compute a large volume of biological sequence data sets through markedly improved storage-handling capabilities (up to 18 terabyte on a 64-bit mode), which were not tractable in any other parallel or single multiple sequence alignment program.

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Download site. http://pchm.inje.ac.kr/clustalxeed

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Download Mirror Site :
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http://www.mediafire.com/?thypv8h3dxzc9q1    ClustalXeed-1.0.tar.gz  (linux version)
http://www.mediafire.com/?7nr42a443ugwmf6   ClustalXeed-Manual-1a.pdf (including installation)

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Reference: Kim T, Joo H: ClustalXeed: a GUI-based grid computation version for high performance and terabyte size multiple sequence alignment, BMC Bioinformatics 2010, 11:467. Article URL http://www.biomedcentral.com/1471-2105/11/467

ClustalXeed Launched !

http://www.biowizard.com/search.php?search=clustalxeed

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